Description

Pyrazine, 2-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]- is a specialized heterocyclic organic compound that serves as a versatile and high-value synthetic intermediate. Its molecular architecture, featuring both a pyrazine ring and a chloromethyl-substituted oxadiazole moiety, makes it a critical building block for constructing complex pharmacologically active molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) agents, antiviral compounds, and anti-inflammatory medications.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of chemical probes, affinity tags, and bioconjugation reagents for studying biological systems.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and medicinal chemistry within university and CRO laboratories.

Basic Information

Product Name	Pyrazine, 2-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]-
CAS No.	114346-91-7
Molecular Formula	C7H5ClN4O
Molecular Weight	196.59 g/mol
Synonyms	2-(5-(Chloromethyl)-1,2,4-oxadiazol-3-yl)pyrazine; 3-Pyrazinyl-5-(chloromethyl)-1,2,4-oxadiazole; 5-(Chloromethyl)-3-(pyrazin-2-yl)-1,2,4-oxadiazole; 1,2,4-Oxadiazole, 5-(chloromethyl)-3-(2-pyrazinyl)-; Pyrazine, 2-(5-(chloromethyl)-1,2,4-oxadiazol-3-yl)-; 2-(5-Chloromethyl-[1,2,4]oxadiazol-3-yl)-pyrazine
EINECS	Contact for details

Quality Control

Every batch of Pyrazine, 2-[5-(Chloromethyl)-1,2,4-Oxadiazol-3-Yl]- is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity research specifications, with comprehensive testing via HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with the agreed specifications. We support cGMP-compliant production for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.