Description

Dofen CAS NO 114265-20-2 is a specialized chemical intermediate of significant interest in advanced organic synthesis. Its unique molecular structure makes it a valuable building block for creating complex molecules with targeted functionalities. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators requiring specific chiral or steric properties.
• Ligand and Catalyst Development: Serves as a foundational structure for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle formation.
• Fine Chemical Production: Utilized in the custom synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	Dofen
CAS No.	114265-20-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Dofen; 1,3-Dioxolane-4,5-dimethanol, 2,2-dimethyl-; 2,2-Dimethyl-1,3-dioxolane-4,5-dimethanol; 4,5-Bis(hydroxymethyl)-2,2-dimethyl-1,3-dioxolane; (4R,5R)-(-)-2,2-Dimethyl-α,α,α',α'-tetramethyl-1,3-dioxolane-4,5-dimethanol (stereoisomer); A chiral dioxolane derivative.
EINECS	Contact for details

Quality Control

Every batch of Dofen (CAS 114265-20-2) is manufactured under a strict quality management system. Our products undergo rigorous analytical testing to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC or GC), chiral purity (where applicable), and impurity profiles is provided with each shipment to guarantee reliable performance in your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.