Description

Dexpemedolac CAS NO 114030-44-3 is a high-purity pharmaceutical intermediate and active ingredient. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of non-steroidal anti-inflammatory drugs (NSAIDs). It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions engaged in advanced drug synthesis and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced NSAID candidates and related anti-inflammatory compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structure for the development and scale-up of new drug formulations.
• Biochemical Research: Used in pharmacological studies to investigate mechanisms of action related to cyclooxygenase (COX) inhibition.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Utilized in route scouting and optimization for efficient, scalable manufacturing processes.

Basic Information

Product Name	Dexpemedolac
CAS No.	114030-44-3
Molecular Formula	C15H13NO3
Molecular Weight	255.27 g/mol
Synonyms	(+)-Pemedolac; Dexibuprofen picolyl ester; Dexpemedolac; (2S)-2-[4-(2-Methylpropyl)phenyl]propanoic acid (pyridin-2-yl)methyl ester; (S)-2-(4-Isobutylphenyl)propionic acid 2-pyridylmethyl ester; UNII-6Q5U0C8Q0C; 6Q5U0C8Q0C
EINECS	Contact for details

Quality Control

Our Dexpemedolac is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client or regulatory standards (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.