Description

Precorrin 3 is a key intermediate compound in the biosynthesis of vitamin B12 and related corrinoids. Its availability is critical for research and development in synthetic biology, enzymatic studies, and the production of complex cofactors. This high-purity intermediate is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focusing on metabolic pathway engineering and advanced cofactor synthesis.

Application

• Biochemical Research: Essential intermediate for studying the complex enzymatic pathway of vitamin B12 (cobalamin) biosynthesis.
• Enzymology Studies: Used as a substrate to investigate the function and kinetics of enzymes like Precorrin-3B C17-methyltransferase (CobM).
• Synthetic Biology: A critical building block in engineered microbial pathways aimed at the fermentative production of cobalamin or its analogs.
• Pharmaceutical R&D: Serves as a reference standard and starting material for the development of novel corrinoid-based therapeutics or diagnostics.
• Cofactor Synthesis: Used in the laboratory-scale synthesis of specialized vitamin B12 derivatives and cofactors for industrial enzymes.
• Metabolic Pathway Analysis: A tool for tracing and understanding corrinoid metabolism in various microorganisms.

Basic Information

Product Name	Precorrin 3
CAS No.	114019-24-8
Molecular Formula	C46H64N4O14
Molecular Weight	897.02 g/mol
Synonyms	Precorrin-3; 1,2,3,5,6,7,8,12,13,15,16,17-Dodecahydro-17-methyl-13-(1-methyl-2-oxo-2-((3,5,9,13-tetramethyl-4,8,12,16-tetraoxo-17-oxa-2-aza-3,5,9,13-tetradecatetraen-1-yl)oxy)ethyl)-21H-bilin-8-propanoic acid; Precorrin 3A; Vitamin B12 biosynthesis intermediate; Corrinoid precursor
EINECS	Contact for details

Quality Control

Our Precorrin 3 is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant standards for fine chemical and biochemical intermediates to support reliable and reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive and should be handled under controlled conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.