Description

1-Palmitoyl-2-Thiopalmitoyl Phosphatidylcholine is a synthetic, sulfur-modified phospholipid analog designed for advanced research and development applications. This specialized compound is valued for its unique thioester linkage, which provides distinct chemical and physical properties compared to its native counterpart. It is primarily utilized by researchers in the fields of lipidomics, membrane biophysics, and pharmaceutical formulation for studying membrane dynamics and developing novel drug delivery systems.

Application

• Biophysical Research: As a key component in model membrane systems (e.g., liposomes, bilayers) for studying lipid-protein interactions, membrane fluidity, and phase behavior.
• Drug Delivery Development: Used in the formulation of specialized liposomal carriers where the thioester bond can influence stability, release kinetics, and targeting capabilities.
• Chemical Biology Probes: Serves as a building block for synthesizing labeled or functionalized phospholipids to track cellular uptake and metabolism.
• Material Science: Investigation of self-assembling nanostructures and biomimetic materials due to its modified amphiphilic character.
• Analytical Standards: Acts as a high-purity reference standard in mass spectrometry-based lipid analysis and quantification.

Basic Information

Product Name	1-Palmitoyl-2-Thiopalmitoyl Phosphatidylcholine
CAS No.	113881-60-0
Molecular Formula	C39H76NO7PS
Molecular Weight	734.06 g/mol
Synonyms	1-Palmitoyl-2-thiopalmitoyl-sn-glycero-3-phosphocholine; Thio-PC(16:0/16:0); S-Palmitoyl Phosphatidylcholine; Phosphatidylcholine, 1-palmitoyl-2-thiopalmitoyl; Sulfur-containing PC analog; 1,2-dihexadecanoyl-thio-phosphatidylcholine; PC(16:0/16:0)-thioester
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Thiopalmitoyl Phosphatidylcholine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is characterized using advanced analytical techniques including NMR and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (Phosphorus)	≥ 98% of theoretical
Solubility	Soluble in chloroform, methanol, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.