Description

4-Cyanopiperazine-1-Carboxylic Acid tert-Butyl Ester is a versatile and high-purity chemical building block, essential for advanced pharmaceutical synthesis and research. Its core value lies in its protected piperazine scaffold and reactive nitrile group, enabling efficient construction of complex molecules. This compound is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for creating novel drug candidates, particularly in CNS and oncology research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Peptidomimetic Synthesis: Serves as a crucial precursor for creating piperazine-containing peptidomimetics and constrained peptides.
• Ligand and Modifier Development: Employed in the development of specialized ligands, catalysts, and chemical modifiers for various applications.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological pathways and target engagement.

Basic Information

Product Name	4-Cyanopiperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	113534-02-4
Molecular Formula	C10H17N3O2
Molecular Weight	211.26 g/mol
Synonyms	1-Boc-4-cyanopiperazine; tert-Butyl 4-cyanopiperazine-1-carboxylate; 4-Cyano-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester; 1-N-Boc-4-cyanopiperazine; 4-Cyano-N-Boc-piperazine; Piperazine-1-carboxylic acid, 4-cyano-, 1,1-dimethylethyl ester; 4-CN-Pip-Boc
EINECS	Contact for details

Quality Control

Our 4-Cyanopiperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.