Description

2-Oxa-3-Deoxy-25-Hydroxyvitamin D3 is a chemically modified analog of vitamin D, designed for advanced research and pharmaceutical development. This compound is valued for its specific structural modifications, which allow scientists to probe and modulate vitamin D receptor (VDR) signaling pathways with high precision. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors for investigating metabolic bone diseases, cancer, and immune system regulation.

Application

• Pharmaceutical Research & Development: A key intermediate or reference standard in the synthesis and study of novel vitamin D receptor (VDR) modulators for therapeutic applications.
• Biochemical Research: Used as a molecular tool to investigate the structure-activity relationships (SAR) of vitamin D analogs and their interaction with biological targets.
• Metabolic Disease Studies: Employed in preclinical research focused on calcium homeostasis, bone mineralization, and disorders such as osteoporosis and rickets.
• Oncology Research: Investigated for its potential role in cell differentiation, proliferation, and apoptosis in various cancer cell lines.
• Immunology Research: Applied in studies exploring the immunomodulatory effects of vitamin D analogs on the immune system.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	2-Oxa-3-Deoxy-25-Hydroxyvitamin D3
CAS No.	113490-39-4
Molecular Formula	C₂₇H₄₂O₃
Molecular Weight	414.62 g/mol
Synonyms	2-Oxa-1α,25-dihydroxy-3-deoxyvitamin D3; 1α,25-Dihydroxy-2-oxa-3-deoxyvitamin D3; 2-Oxa-3-deoxy-1α,25-dihydroxycholecalciferol; 2-Oxa-3-deoxycalcitriol analog; OCT analog; Vitamin D3 analog; 2-Oxa-3-deoxy-1α,25-(OH)₂D₃
EINECS	Contact for details

Quality Control

Our 2-Oxa-3-Deoxy-25-Hydroxyvitamin D3 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label or COA. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.