Description

n-[4-(Piperazin-1-Yl)Phenyl]Methanesulfonamide Hydrochloride is a high-purity, specialized organic intermediate of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel bioactive molecules, particularly those targeting central nervous system and oncological pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Chemical Biology Research: Used as a scaffold or probe in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the development of new chemical entities (NCEs).
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs engaged in custom synthesis and process scale-up projects.

Basic Information

Product Name	n-[4-(Piperazin-1-Yl)Phenyl]Methanesulfonamide Hydrochloride
CAS No.	112940-54-2
Molecular Formula	C11H18N4O2S • HCl
Molecular Weight	306.81 g/mol
Synonyms	4-(4-(Methylsulfonamido)phenyl)piperazine hydrochloride; N-(4-Piperazin-1-ylphenyl)methanesulfonamide hydrochloride; 1-[4-[(Methylsulfonyl)amino]phenyl]piperazine hydrochloride; Methanesulfonamide, N-[4-(1-piperazinyl)phenyl]-, hydrochloride; UNII-9J2S7I4UQJ; 112940-54-2; 4-(Piperazin-1-yl)phenyl methanesulfonamide HCl
EINECS	Contact for details

Quality Control

Our n-[4-(Piperazin-1-Yl)Phenyl]Methanesulfonamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.