Description

16-Hydroxy Capsaicin is a hydroxylated derivative of the well-known pungent compound capsaicin, offering a distinct chemical profile for advanced research and development. This specialized analog is valued for its potential to modulate biological activity with altered potency and metabolic pathways compared to its parent molecule. It serves as a critical intermediate and reference standard for pharmaceutical, nutraceutical, and agrochemical innovators exploring novel TRPV1 channel modulators, anti-inflammatory agents, and bioactive natural product derivatives.

Application

• Pharmaceutical Research: Key intermediate in the synthesis of novel analgesic and anti-inflammatory drug candidates targeting vanilloid receptors (TRPV1).
• Reference Standard: High-purity analytical standard for quality control and method development in the analysis of capsaicinoid mixtures and metabolites.
• Nutraceutical Development: Investigational ingredient for studying modified bioactivity and bioavailability in functional food and dietary supplement formulations.
• Agrochemical Studies: Research compound for developing next-generation, naturally-derived pest deterrents and animal repellents with tailored properties.
• Biochemical Research: Tool compound for probing structure-activity relationships (SAR) of capsaicinoids in neurobiology and pain signaling pathways.
• Cosmeceutical Applications: Investigated for potential use in topical formulations aimed at skin sensitization, circulation, and metabolic studies.

Basic Information

Product Name	16-Hydroxy Capsaicin
CAS No.	112848-19-8
Molecular Formula	C18H27NO4
Molecular Weight	321.41 g/mol
Synonyms	16-Hydroxy-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methyl-6-nonenamide; Capsaicin, 16-hydroxy-; 16-Hydroxycapsaicin; 16-Hydroxy-Dihydrocapsaicin; (6E)-N-(4-Hydroxy-3-methoxybenzyl)-8-methyl-6-nonenamide-16-ol
EINECS	Contact for details

Quality Control

Our 16-Hydroxy Capsaicin is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.