Description

1-(4-Methoxy-Phenyl)-1,2,3,4-Tetrahydro-Pyrrolo[1,2-A]Pyrazine CAS NO 112758-90-4 is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrazine class of heterocyclic compounds. Its core value lies in its role as a critical building block for synthesizing complex active pharmaceutical ingredients (APIs) with potential therapeutic applications. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Organic Synthesis Building Block: Used in multi-step synthesis for constructing complex nitrogen-containing heterocycles due to its fused pyrrolopyrazine structure.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of potential therapeutics.
• Process Development & Scale-Up: Employed in the optimization and kilogram-scale production of target molecules for clinical trials.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of investigational and commercial APIs.
• Academic & Institutional Research: Utilized in university and institutional labs for pioneering research in synthetic methodology and drug discovery.

Basic Information

Product Name	1-(4-Methoxy-Phenyl)-1,2,3,4-Tetrahydro-Pyrrolo[1,2-A]Pyrazine
CAS No.	112758-90-4
Molecular Formula	C15H18N2O
Molecular Weight	242.32 g/mol
Synonyms	1-(4-Methoxyphenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine; 1-(4-Methoxyphenyl)-1,2,3,4-tetrahydro-pyrrolo[1,2-a]pyrazine; 1-(4-Methoxy-phenyl)-1,2,3,4-tetrahydro-pyrrolo[1,2-a]pyrazine; Pyrrolo[1,2-a]pyrazine, 1-(4-methoxyphenyl)-1,2,3,4-tetrahydro-; 1-(4-Methoxyphenyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine; 112758-90-4; 1-(4-Methoxy-Phenyl)-1,2,3,4-Tetrahydro-Pyrrolo[1,2-A]Pyrazine
EINECS	Contact for details

Quality Control

Our 1-(4-Methoxy-Phenyl)-1,2,3,4-Tetrahydro-Pyrrolo[1,2-A]Pyrazine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications and can support customer audits and regulatory filings. Our quality commitment aligns with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.