Description

1,3-Dioxolane-4-Carboxaldehyde, 2,2,5-Trimethyl-, (4R-Cis)- (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its unique stereochemistry and functional groups make it a valuable precursor for constructing complex molecular architectures, particularly in the pharmaceutical sector. This compound is essential for research and development chemists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where precise stereocontrol is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides with specific stereochemical activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new chiral catalysts and methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high enantiomeric purity.
• Academic & Industrial R&D: A critical reagent for synthetic organic chemists in universities and corporate labs exploring new reaction pathways and natural product synthesis.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2,2,5-Trimethyl-, (4R-Cis)- (9Ci)
CAS No.	112709-74-7
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(4R-cis)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxaldehyde; (4R,5S)-2,2,5-Trimethyl-1,3-dioxolane-4-carbaldehyde; (4R,5S)-2,2,5-Trimethyl-1,3-dioxolane-4-carboxaldehyde; 2,2,5-Trimethyl-1,3-dioxolane-4-carboxaldehyde, (4R-cis)-; (4R,5S)-4-Formyl-2,2,5-trimethyl-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxaldehyde, 2,2,5-Trimethyl-, (4R-Cis)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.