Description

2-Eicosapentaenoyl-Sn-Glycerol-3-Phosphocholine is a specialized, high-purity phospholipid derivative of eicosapentaenoic acid (EPA), a critical ω-3 fatty acid. This compound serves as a vital biochemical tool and a premium-grade raw material for advanced research and formulation development. It is primarily required by pharmaceutical, nutraceutical, and life science research sectors for its role in lipidomics, membrane biology studies, and the development of targeted lipid-based delivery systems.

Application

• Pharmaceutical Research & Development: Used as a reference standard and an active pharmaceutical ingredient (API) intermediate in the development of novel lipid-based therapeutics.
• Lipidomics & Biomarker Studies: A critical analytical standard for the identification and quantification of complex phospholipids in biological samples using LC-MS/MS techniques.
• Liposome & Nanoparticle Formulation: Acts as a functional excipient to create specialized liposomal carriers for targeted drug delivery, enhancing bioavailability and cellular uptake.
• Cell Culture & Membrane Biology: Employed to modulate membrane fluidity and study the functional roles of EPA-containing phospholipids in cellular signaling pathways.
• Nutraceutical Advanced Formulations: Incorporated into high-end dietary supplements designed for superior bioavailability of ω-3 fatty acids in phospholipid form.
• Biochemical Reagent: Serves as a substrate for enzymes like phospholipases in enzymatic assays and metabolic pathway investigations.

Basic Information

Product Name	2-Eicosapentaenoyl-Sn-Glycerol-3-Phosphocholine
CAS No.	112667-21-7
Molecular Formula	C30H54NO8P
Molecular Weight	587.73 g/mol
Synonyms	1-Eicosapentaenoyl-2-hydroxy-sn-glycero-3-phosphocholine; EPA-lysoPC; LysoPC(20:5(5Z,8Z,11Z,14Z,17Z)); 1-(5Z,8Z,11Z,14Z,17Z-Eicosapentaenoyl)-2-hydroxy-sn-glycero-3-phosphocholine; Lysophosphatidylcholine (20:5); LysoPEA; 2-Hydroxy-3-phosphocholine propanoate eicosapentaenoate
EINECS	Contact for details

Quality Control

Our 2-Eicosapentaenoyl-Sn-Glycerol-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in chloroform, methanol; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.