Description

(+/-)5-Hepe CAS NO 112572-25-5 is a high-purity synthetic hydroxy fatty acid derivative, specifically a 5-hydroxy derivative of eicosapentaenoic acid (EPA). This compound serves as a valuable biochemical research tool and a key intermediate in the synthesis of specialized lipid mediators and bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on inflammation, metabolic pathways, and lipidomics.

Application

• Biochemical Research: Used as a reference standard and precursor in studies of eicosanoid and specialized pro-resolving mediator (SPM) biosynthesis pathways.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis of novel anti-inflammatory and immunomodulatory drug candidates.
• Lipidomics & Metabolomics: Employed as an analytical standard for the identification and quantification of hydroxy fatty acids in complex biological samples.
• Cell Signaling Studies: Applied in vitro to investigate the role of hydroxy-EPA derivatives in cellular signaling and receptor interactions.
• Fine Chemical Synthesis: Acts as a building block for the preparation of more complex, stereochemically defined lipid molecules for research purposes.

Basic Information

Product Name	(+/-)5-Hepe
CAS No.	112572-25-5
Molecular Formula	C20H30O3
Molecular Weight	318.45 g/mol
Synonyms	5-Hydroxy-5,8,11,14,17-eicosapentaenoic acid; 5-HEPE; (±)-5-HEPE; all-cis-5-Hydroxy-5,8,11,14,17-eicosapentaenoic acid; 5-Hydroxy-EPA; 5-Hydroxy-eicosapentaenoic acid; 5-Hydroxyicosa-5,8,11,14,17-pentaenoic acid
EINECS	Contact for details

Quality Control

Our (+/-)5-Hepe is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided to ensure traceability and compliance with research-grade specifications. We support cGMP and ISO-guided practices for consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by weight)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.