Description

1-Piperazinecarbonylchloride,4-Methyl-3,5-Dioxo-(9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of complex pharmacologically active molecules, offering a reactive scaffold for constructing diverse chemical libraries. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in high-throughput screening and combinatorial chemistry to create novel compound libraries for biological evaluation.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules during drug development.
• Agrochemical Synthesis: Acts as a precursor in the development of new pesticides and herbicides with specific biological activity.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry, reaction mechanisms, and new synthetic methodologies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	1-Piperazinecarbonylchloride,4-Methyl-3,5-Dioxo-(9Ci)
CAS No.	112489-86-8
Molecular Formula	C7H9ClN2O3
Molecular Weight	204.61 g/mol
Synonyms	4-Methyl-3,5-dioxopiperazine-1-carbonyl chloride; 1-(Chlorocarbonyl)-4-methyl-2,6-piperazinedione; 4-Methyl-2,6-dioxopiperazine-1-carbonyl chloride; 4-Methyl-3,5-dioxo-1-piperazinecarbonyl chloride; 1-Carbamoyl-4-methylpiperazine-2,6-dione chloride; 4-Methyl-2,6-dioxopiperazine-1-carboxylic acid chloride; 1-Piperazinecarbonyl chloride, 4-methyl-3,5-dioxo-
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarbonylchloride,4-Methyl-3,5-Dioxo-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.