Description

(3S)-5β-(β-D-Glucopyranosyloxy)-3,3Aβ,4,5,9Aβ,9Bα-Hexahydro-3β,6,9-Trimethylazuleno[4,5-B]Furan-2,7-Dione is a complex sesquiterpene lactone glycoside with a unique azulene-fused furandione structure. This high-purity compound is of significant interest for advanced research and development in pharmaceutical chemistry, particularly for its potential bioactivity. It serves as a critical intermediate or reference standard for scientists in medicinal chemistry, natural product synthesis, and pharmacology. The compound, identified by CAS No. 112408-66-9, is supplied to meet the stringent requirements of laboratory and pilot-scale applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting anti-inflammatory or anticancer pathways.
• Medicinal Chemistry Research: Used as a reference compound or a starting material for structure-activity relationship (SAR) studies and lead optimization.
• Natural Product Synthesis: Acts as a sophisticated intermediate in the total or semi-synthesis of complex natural products for academic and industrial research.
• Biochemical Research: Employed in enzymatic and receptor-binding assays to investigate specific biological mechanisms and interactions.
• Analytical Reference Standard: Provides a high-purity standard for method development and quality control in analytical laboratories (HPLC, LC-MS).
• Preclinical Development: Utilized in early-stage in vitro and in vivo studies to evaluate pharmacokinetics and efficacy.

Basic Information

Product Name	(3S)-5β-(β-D-Glucopyranosyloxy)-3,3Aβ,4,5,9Aβ,9Bα-Hexahydro-3β,6,9-Trimethylazuleno[4,5-B]Furan-2,7-Dione
CAS No.	112408-66-9
Molecular Formula	C₂₃H₃₀O₉
Molecular Weight	450.48 g/mol
Synonyms	5β-(β-D-Glucopyranosyloxy)-3,3aβ,4,5,9aβ,9bα-hexahydro-3β,6,9-trimethylazuleno[4,5-b]furan-2,7-dione; (3S)-Azuleno[4,5-b]furan-2,7-dione, 5-(β-D-glucopyranosyloxy)-3,3a,4,5,9a,9b-hexahydro-3,6,9-trimethyl-, (3S,3aR,5S,9aR,9bS)-; Sesquiterpene lactone glycoside; Azulene glycoside derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (3S)-5β-(β-D-Glucopyranosyloxy)-3,3Aβ,4,5,9Aβ,9Bα-Hexahydro-3β,6,9-Trimethylazuleno[4,5-B]Furan-2,7-Dione is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets exacting specifications for research use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere to preserve stability. Keep the container sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.