Description

Liposyn Ii is a sterile, non-pyrogenic fat emulsion for intravenous administration, primarily used as a source of calories and essential fatty acids. It is a critical component in parenteral nutrition regimens, providing vital energy and preventing essential fatty acid deficiency in patients unable to receive adequate nutrition orally. This product is essential for hospitals, clinical nutrition providers, and compounding pharmacies serving patients in critical care, post-operative recovery, and long-term nutritional support.

Application

• Parenteral Nutrition (PN): A primary component of total parenteral nutrition (TPN) or peripheral parenteral nutrition (PPN) formulations to deliver concentrated calories.
• Essential Fatty Acid (EFA) Supplementation: Prevents and treats essential fatty acid deficiency (EFAD) in patients on long-term fat-free intravenous feeding.
• Critical Care Medicine: Provides a dense, readily metabolizable energy source for critically ill, catabolic patients in intensive care units (ICUs).
• Post-operative Nutritional Support: Supports recovery and wound healing in surgical patients with compromised gastrointestinal function.
• Oncology and Cachexia Management: Helps maintain or improve nutritional status in cancer patients experiencing cachexia or malabsorption.
• Pediatric and Neonatal Nutrition: Used in specially formulated parenteral nutrition for infants and children with intestinal failure.
• Home Parenteral Nutrition (HPN): A key ingredient for patients requiring long-term nutritional support outside of a hospital setting.

Basic Information

Product Name	Liposyn Ii
CAS No.	112353-79-4
Molecular Formula	Complex emulsion; primarily composed of Safflower Oil and Soybean Oil triglycerides.
Molecular Weight	N/A (Emulsion)
Synonyms	Liposyn II; Intravenous Fat Emulsion; IV Fat Emulsion; Parenteral Fat Emulsion; Safflower Oil and Soybean Oil Emulsion; 10% or 20% Lipid Injectable Emulsion; IVFE; Fat Emulsion for Injection.
EINECS	Contact for details

Quality Control

Manufactured under strict cGMP (current Good Manufacturing Practice) conditions, Liposyn Ii is subject to rigorous quality testing to ensure it meets or exceeds USP (United States Pharmacopeia) and FDA standards for injectable emulsions. Every batch is tested for critical parameters including sterility, apyrogenicity, particle size distribution, pH, and fatty acid composition. A comprehensive Certificate of Analysis (COA) is available for each lot to guarantee product integrity and traceability.

Storage

Preserve in the original, unopened container. Store at controlled room temperature, 20°C to 25°C (68°F to 77°F). Excursions are permitted between 15°C and 30°C (59°F and 86°F). Do not freeze. Protect from light. Do not use if there is evidence of oil separation or cracking of the emulsion.

Specification

Item	Specification
Description	White, sterile, non-pyrogenic fat emulsion
Concentration	10% or 20% w/v
Primary Oils	Safflower Oil, Soybean Oil
pH	6.0 - 8.5
Mean Particle Size (Fat Globules)	< 0.5 µm
Large Particle Limit (PFAT5)	Meets USP <788> requirements
Sterility	Sterile (Tested per USP <71>)
Endotoxins / Pyrogens	< 0.5 EU/mL (Tested per USP <85>)
Osmolality	Approx. 300 mOsm/kg (isotonic)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.