Description

Piperazinone, 4-[(Aminooxy)Acetyl]- (9Ci) CAS NO 112257-43-9 is a specialized organic compound featuring a piperazinone core functionalized with an aminooxyacetyl group. This unique structure makes it a valuable high-purity building block and key intermediate in advanced synthetic chemistry. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Bioconjugation & Linker Chemistry: The aminooxyacetyl moiety is utilized for site-specific conjugation of molecules, such as in antibody-drug conjugate (ADC) development and peptide modification.
• Chemical Biology Research: Used as a tool compound or building block for probing biological systems and developing chemical probes.
• Agrochemical Synthesis: Acts as an intermediate in the development of advanced crop protection agents and herbicides.
• Material Science Research: Employed in the synthesis of functional polymers and specialty materials requiring specific molecular recognition sites.
• Academic & Contract Research: Essential for research institutions and CROs (Contract Research Organizations) engaged in cutting-edge organic and medicinal chemistry projects.

Basic Information

Product Name	Piperazinone, 4-[(Aminooxy)Acetyl]- (9Ci)
CAS No.	112257-43-9
Molecular Formula	C7H13N3O3
Molecular Weight	187.20 g/mol
Synonyms	4-[(Aminooxy)acetyl]piperazin-2-one; 1,4-Diazinan-2-one, 4-[(aminooxy)acetyl]-; 4-(Aminooxyacetyl)piperazin-2-one; 4-(2-Aminooxyacetyl)piperazin-2-one; 4-(Carboxymethoxyamino)piperazin-2-one; Aminooxyacetyl piperazinone; N-(Aminooxyacetyl)piperazinone; Piperazin-2-one, 4-[(aminooxy)acetyl]-
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure the integrity of this high-value intermediate. Each batch is characterized and tested to confirm identity and purity, with specifications tailored to meet the stringent requirements of research and cGMP (current Good Manufacturing Practice) environments. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing analytical results from techniques including HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.