Description

4-Boc-2-Piperazinecarboxamide is a protected piperazine derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its primary value lies in providing a versatile, nitrogen-containing scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), especially within the fields of central nervous system (CNS) agents and protease inhibitors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting various therapeutic areas.
• Protease Inhibitor Development: Used in the research and production of protease inhibitors for antiviral and other therapeutic applications.
• CNS Drug Synthesis: Serves as a precursor in the manufacture of compounds designed to interact with central nervous system receptors.
• Peptidomimetic Chemistry: Integral for creating peptide-like molecules with enhanced stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for custom chemical synthesis projects.
• Academic & Industrial R&D: Utilized in discovery chemistry for exploring new chemical entities and structure-activity relationships.

Basic Information

Product Name	4-Boc-2-Piperazinecarboxamide
CAS No.	112257-24-6
Molecular Formula	C10H19N3O3
Molecular Weight	229.28 g/mol
Synonyms	tert-Butyl 4-carbamoylpiperazine-1-carboxylate; 1-Boc-4-carbamoylpiperazine; 1-(tert-Butoxycarbonyl)-4-carbamoylpiperazine; 4-Carbamoyl-1-piperazinecarboxylic Acid tert-Butyl Ester; 1-N-Boc-4-carbamoylpiperazine; Piperazine-1,4-dicarboxamide, 1-(tert-butoxycarbonyl)-; 4-(Aminocarbonyl)-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our 4-Boc-2-Piperazinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients' pharmaceutical development and manufacturing needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.