Description

tert-Butyl2-(Piperazin-1-Yl)Acetate is a high-purity chemical intermediate of significant importance in advanced organic synthesis. This compound serves as a versatile building block, enabling the efficient introduction of a protected piperazinyl-acetate moiety into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require a piperazine-based scaffold.
• Chemical Research & Development: Employed as a versatile reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Peptidomimetic Chemistry: Serves as a building block for creating peptide analogs and mimetics with enhanced metabolic stability and bioavailability.
• Ligand Synthesis: Useful in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	tert-Butyl2-(Piperazin-1-Yl)Acetate
CAS No.	112257-22-4
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	1-(tert-Butoxycarbonylmethyl)piperazine; tert-Butyl (piperazin-1-yl)acetate; 2-(1-Piperazinyl)acetic acid 1,1-dimethylethyl ester; 1-Piperazineacetic acid, 1,1-dimethylethyl ester; Acetic acid, 2-(1-piperazinyl)-, 1,1-dimethylethyl ester; BOC-Pip-CH2-CO2tBu; tert-Butyl 2-(piperazin-1-yl)acetate hydrochloride (salt forms); N-Boc-piperazinylacetic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl2-(Piperazin-1-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.