Description

Quinoxaline, 6-Bromo-2-Fluoro- is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique bromo-fluoro substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoxaline core.
• Material Science Precursor: Serves as a monomer or functional unit in the creation of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to create diverse compound libraries.
• Academic & Contract Research: A valuable reagent for methodological development and synthetic chemistry research in academic and contract research organizations (CROs).

Basic Information

Product Name	Quinoxaline, 6-Bromo-2-Fluoro-
CAS No.	112080-07-6
Molecular Formula	C8H4BrFN2
Molecular Weight	227.04 g/mol
Synonyms	6-Bromo-2-fluoroquinoxaline; 2-Fluoro-6-bromoquinoxaline; Quinoxaline, 6-bromo-2-fluoro-; 6-Bromo-2-fluoro-quinoxaline; 112080-07-6; 6-Br-2-F-quinoxaline; 2-Fluoro-6-bromo-1,4-diazanaphthalene
EINECS	Contact for details

Quality Control

Our Quinoxaline, 6-Bromo-2-Fluoro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.