Description

2-[4-(2-Hydroxyethyl)-1-Piperazinyl]Nicotinic Acid is a high-purity, functionalized piperazine derivative with a nicotinic acid core. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents, particularly those targeting neurological and cardiovascular pathways. It is essential for research and development chemists, process development scientists, and manufacturers in the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Biochemical Research: Used as a precursor or ligand in medicinal chemistry research for developing new therapeutic candidates.
• Fine Chemical Synthesis: Serves as a versatile intermediate for creating complex molecules with specific biological activity in contract research and manufacturing organizations (CROs/CMOs).
• Ligand and Chelator Development: Its structure makes it suitable for developing chelating agents or ligands in catalytic and diagnostic applications.

Basic Information

Product Name	2-[4-(2-Hydroxyethyl)-1-Piperazinyl]Nicotinic Acid
CAS No.	111855-51-7
Molecular Formula	C12H17N3O3
Molecular Weight	251.28 g/mol
Synonyms	2-(4-(2-Hydroxyethyl)piperazin-1-yl)nicotinic acid; 2-[4-(2-Hydroxyethyl)-1-piperazinyl]-3-pyridinecarboxylic acid; 2-(4-(2-Hydroxyethyl)piperazin-1-yl)pyridine-3-carboxylic acid; Nicotinic acid, 2-[4-(2-hydroxyethyl)-1-piperazinyl]-; 111855-51-7; 2-(4-(2-Hydroxyethyl)piperazino)nicotinic acid
EINECS	Contact for details

Quality Control

Our 2-[4-(2-Hydroxyethyl)-1-Piperazinyl]Nicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.