Description

2-(1,1-Difluoroethyl)Pyrazine is a specialized fluorinated heterocyclic compound that serves as a high-value building block in advanced chemical synthesis. Its unique structure, featuring a difluoroethyl side chain on a pyrazine core, makes it a critical intermediate for introducing specific fluorine motifs into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where fluorine atoms improve metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and electronic materials to modify surface properties and dielectric constants.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex, nitrogen-containing aroma compounds, though typically at high purity grades.

Basic Information

Product Name	2-(1,1-Difluoroethyl)Pyrazine
CAS No.	111781-49-8
Molecular Formula	C6H6F2N2
Molecular Weight	144.12 g/mol
Synonyms	1-(1,1-Difluoroethyl)pyrazine; 2-(1,1-Difluoroethyl)-1,4-diazine; Pyrazine, 2-(1,1-difluoroethyl)-; 1,1-Difluoro-1-(pyrazin-2-yl)ethane; Difluoroethylpyrazine; 2-(α,α-Difluoroethyl)pyrazine
EINECS	Contact for details

Quality Control

Every batch of 2-(1,1-Difluoroethyl)Pyrazine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and process development. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profile via techniques such as GC, HPLC, NMR, and MS, is supplied with each shipment to guarantee reproducible results and supply chain integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.