Description

4-(3-Ethylamino-Pyridin-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value, nitrogen-rich heterocyclic building block used in advanced organic synthesis. This compound is critical for research and development in the pharmaceutical sector, particularly in the construction of complex molecules with targeted biological activity. It is primarily sought after by medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs) and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing piperazine- and pyridine-containing libraries for structure-activity relationship (SAR) studies and high-throughput screening.
• API Development: Used in the research and process development stages for creating active pharmaceutical ingredients that require this specific substituted piperazine moiety.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global pharmaceutical market.

Basic Information

Product Name	4-(3-Ethylamino-Pyridin-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	111669-26-2
Molecular Formula	C16H26N4O2
Molecular Weight	306.41 g/mol
Synonyms	tert-Butyl 4-(3-(ethylamino)pyridin-2-yl)piperazine-1-carboxylate; 1-Boc-4-(3-ethylaminopyridin-2-yl)piperazine; 4-(3-Ethylamino-2-pyridyl)-1-piperazinecarboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-(ethylamino)pyridin-2-yl)piperazine; 111669-26-2; N-Ethyl-N'-(1-Boc-piperazin-4-yl)-3-aminopyridine
EINECS	Contact for details

Quality Control

Our production of 4-(3-Ethylamino-Pyridin-2-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.