Description

Ethyl 1-(Phenylsulfonyl)-4-Piperidinecarboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in modern organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of complex molecules with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those containing piperidine and sulfonamide pharmacophores.
• Organic Synthesis Building Block: Used in multi-step synthetic routes for constructing nitrogen-containing heterocycles and functionalized piperidine derivatives.
• Agrochemical Research: Employed in the research and development of new pesticides and herbicides due to its specific chemical scaffold.
• Chemical Biology Probe Development: Serves as a starting material for creating molecular probes to study biological pathways and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Ethyl 1-(Phenylsulfonyl)-4-Piperidinecarboxylate
CAS No.	111627-26-0
Molecular Formula	C14H19NO4S
Molecular Weight	297.37 g/mol
Synonyms	Ethyl 1-(Phenylsulfonyl)piperidine-4-carboxylate; 4-(Ethoxycarbonyl)-1-(phenylsulfonyl)piperidine; 1-(Phenylsulfonyl)piperidine-4-carboxylic Acid Ethyl Ester; 1-Benzenesulfonyl-piperidine-4-carboxylic acid ethyl ester; NSC 339586; Ethyl N-(Phenylsulfonyl)isonipecotate
EINECS	Contact for details

Quality Control

Our Ethyl 1-(Phenylsulfonyl)-4-Piperidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail specifications including assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH limits
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.