Description

1-o-(12-(2-Naphthyl)Dodec-11-Enyl)-2-o-Decanoyl-Sn-Glycerol-3-Phosphocholine is a specialized synthetic phospholipid derivative, a key building block in advanced lipid research and formulation. This compound is valued for its unique structural features, including a naphthyl-modified alkyl chain and a defined sn-2 decanoyl group, which allow for precise modulation of membrane properties and targeted delivery systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing novel liposomal drug carriers, model membrane systems, and diagnostic agents.

Application

• Liposomal Drug Delivery Systems: As a functionalized phospholipid for constructing targeted and stealth liposomes to improve drug solubility, stability, and biodistribution.
• Biomimetic Membrane Research: For creating specialized model membranes (e.g., vesicles, supported lipid bilayers) to study protein-lipid interactions, membrane fluidity, and signaling.
• Diagnostic Agent Formulation: As a component in the synthesis of contrast agents or probes for imaging techniques such as MRI or fluorescence microscopy.
• Gene Delivery Vectors: Potential use in the formulation of cationic or neutral lipid nanoparticles (LNPs) for nucleic acid encapsulation and delivery.
• Cosmeceutical & Dermal Delivery: In advanced topical formulations where engineered phospholipids enhance skin penetration and stability of active ingredients.
• Biochemical Tool & Standard: As a high-purity reference standard for analytical method development, quality control, and academic research in lipidomics.

Basic Information

Product Name	1-o-(12-(2-Naphthyl)Dodec-11-Enyl)-2-o-Decanoyl-Sn-Glycerol-3-Phosphocholine
CAS No.	111621-45-5
Molecular Formula	C44H74NO8P
Molecular Weight	776.03 g/mol
Synonyms	1-(12-(2-Naphthyl)dodec-11-enyl)-2-decanoyl-sn-glycero-3-phosphocholine; Naphthyl-modified Phosphatidylcholine; PC(10:0/12:0-Naphthyl); 1-O-[12-(2-Naphthalenyl)dodec-11-enyl]-2-O-decanoyl-sn-glycero-3-phosphocholine; Synthetic Phospholipid 111621-45-5; Lyso PC Derivative; Functionalized Glycerophosphocholine; 2-Decanoyl-1-(12-(naphthalen-2-yl)dodec-11-enyl)-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Every batch of our synthetic phospholipids is produced and analyzed under strict quality management protocols. We employ advanced chromatographic (HPLC, LC-MS) and spectroscopic techniques to ensure high chemical and isomeric purity, critical for sensitive research and formulation work. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Chemical Purity (TLC)	Single major spot
Solubility	Soluble in chloroform, methanol, DMSO; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.