Description

5-Bromo-2,3-Dimethylpyrazine is a halogenated pyrazine derivative, a versatile and valuable building block in advanced organic synthesis. Its core value lies in its bromine substituent, which provides a reactive site for cross-coupling reactions and further functionalization, enabling the construction of complex heterocyclic systems. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the pyrazine core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Flavor and Fragrance Industry: Acts as a potential intermediate for creating complex aroma chemicals, given the significance of alkylpyrazines in flavor profiles.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological pathways and protein interactions.

Basic Information

Product Name	5-Bromo-2,3-Dimethylpyrazine
CAS No.	111454-68-3
Molecular Formula	C6H7BrN2
Molecular Weight	187.04 g/mol
Synonyms	2,3-Dimethyl-5-bromopyrazine; 5-Bromo-2,3-dimethylpyrazine; 5-Bromo-2,3-dimethyl-1,4-diazine; Pyrazine, 5-bromo-2,3-dimethyl-; 5-Bromo-2,3-dimethylpyrazine (CAS 111454-68-3)
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Dimethylpyrazine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.