Description

n-(1H-Tetrazol-5-Yl)-6-Chloropyrazine-2-Carboxamide is a specialized heterocyclic compound that serves as a critical building block in advanced organic synthesis. This high-value intermediate is essential for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering unique structural motifs for molecular design. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate tetrazole and chloropyrazine functionalities into new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting cardiovascular, metabolic, and central nervous system disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the tetrazole ring.
• Ligand Synthesis in Coordination Chemistry: Serves as a versatile ligand or precursor for metal-organic frameworks (MOFs) and catalysts due to its multiple nitrogen donor sites.
• Material Science: Investigated for the creation of energetic materials and specialty polymers where the tetrazole group contributes high nitrogen content and stability.
• Chemical Biology Probe Development: Employed in the design of enzyme inhibitors and molecular probes for biochemical research.

Basic Information

Product Name	n-(1H-Tetrazol-5-Yl)-6-Chloropyrazine-2-Carboxamide
CAS No.	111374-47-1
Molecular Formula	C6H4ClN7O
Molecular Weight	225.60 g/mol
Synonyms	6-Chloro-N-(1H-tetrazol-5-yl)pyrazine-2-carboxamide; 6-Chloro-N-(2H-tetrazol-5-yl)pyrazine-2-carboxamide; 6-Chloropyrazine-2-carboxylic acid (1H-tetrazol-5-yl)amide; 111374-47-1; 5-[(6-Chloropyrazine-2-carbonyl)amino]-1H-tetrazole; 6-Chloro-N-(1H-1,2,3,4-tetrazol-5-yl)pyrazine-2-carboxamide
EINECS	Contact for details

Quality Control

Our n-(1H-Tetrazol-5-Yl)-6-Chloropyrazine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.