Description

1-(2-Cyanophenyl)Piperazine is a high-purity, versatile piperazine derivative and a key synthetic intermediate in advanced organic chemistry. This compound matters for its crucial role as a building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific molecular architecture enables targeted synthesis. Pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers need this material for creating novel compounds with potential therapeutic and functional properties. Its consistent quality and reliable supply are essential for streamlining complex multi-step synthesis processes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and psychiatric therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its piperazine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals requiring a specific aromatic-amine structure.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry research programs.
• Material Science: Investigated as a monomer or cross-linking agent in the development of advanced polymers with specific thermal or mechanical properties.

Basic Information

Product Name	1-(2-Cyanophenyl)Piperazine
CAS No.	111373-03-6
Molecular Formula	C11H13N3
Molecular Weight	187.24 g/mol
Synonyms	2-(Piperazin-1-yl)benzonitrile; 1-(2-Cyanophenyl)piperazine; 2-Cyanophenylpiperazine; 2-Piperazin-1-ylbenzonitrile; Benzonitrile, 2-(1-piperazinyl)-; 1-Piperazinyl-2-cyanobenzene; (2-Cyanophenyl)piperazine; 2-(1-Piperazinyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 1-(2-Cyanophenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to guarantee traceability, consistency, and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.