Description

Luffariellolide is a potent marine-derived sesterterpenoid compound with significant biological activity. This high-purity reference standard is critical for pharmaceutical research and development, particularly in the discovery of novel anti-inflammatory and anti-cancer agents. It serves as an essential tool for researchers in drug discovery, natural product chemistry, and molecular biology, enabling the study of complex biochemical pathways.

Application

• Pharmaceutical R&D Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in drug discovery pipelines.
• Anti-inflammatory Agent Research: Investigated for its potent inhibitory effects on phospholipase A2 (PLA2), a key enzyme in the inflammatory cascade.
• Oncology Research: Studied for its cytotoxic properties against various cancer cell lines, supporting the development of new chemotherapeutic candidates.
• Biochemical Pathway Analysis: Employed as a specific probe to study signal transduction pathways involving PLA2 and related lipid mediators.
• Natural Product Isolation & Synthesis: Serves as a benchmark compound for the isolation, structural elucidation, and total synthesis of related marine natural products.
• Academic & Institutional Research: Used in university and government laboratories for fundamental research in chemical ecology and marine pharmacology.

Basic Information

Product Name	Luffariellolide
CAS No.	111149-87-2
Molecular Formula	C₂₅H₃₈O₄
Molecular Weight	402.57 g/mol
Synonyms	(+)-Luffariellolide; Luffariellolide A; Manoalide derivative; 1-[2-[(5R)-5-[(1R)-3-[(2S,5R)-5-[(1R)-1-Hydroxyethyl]oxolan-2-yl]-1-hydroxypropyl]oxolan-2-yl]ethyl]-4-hydroxy-5-methylhex-2-en-1-one
EINECS	Contact for details

Quality Control

Our Luffariellolide is produced under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for reference standards to support your regulatory and publication requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.