Description

5,6-Methano-15-Hydroxy-7,9,11,13-Eicosatetraenoic Acid is a specialized eicosanoid derivative, a class of compounds with significant biological signaling functions. This compound is valued as a high-purity reference standard and a critical synthetic intermediate for advanced biochemical research. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on lipid mediator pathways, inflammation studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, LC-MS) and for method validation in drug development pipelines.
• Biochemical Research: Serves as a key intermediate or probe in studying eicosanoid receptors, enzyme kinetics (e.g., cyclooxygenase, lipoxygenase pathways), and cellular signaling mechanisms.
• Inflammation & Immunology Studies: Applied in vitro and in vivo research to investigate the role of lipid mediators in inflammatory responses and immune regulation.
• Synthetic Chemistry Building Block: Utilized for the custom synthesis of more complex prostaglandin-like molecules and analogs for structure-activity relationship (SAR) studies.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in medicinal chemistry and pharmacology.

Basic Information

Product Name	5,6-Methano-15-Hydroxy-7,9,11,13-Eicosatetraenoic Acid
CAS No.	111037-11-7
Molecular Formula	C₂₁H₃₂O₃
Molecular Weight	332.48 g/mol
Synonyms	15-Hydroxy-5,6-methano-7,9,11,13-eicosatetraenoic acid; 5,6-Methano-PGH₂; 5,6-Methanoprostaglandin H2 analog; 15-Hydroxy-5,6-methanoleukotriene A4; U-44069 (related analog); 5,6-Methano-LTA4 derivative; Eicosatetraenoic acid, 5,6-methano-15-hydroxy-7,9,11,13-
EINECS	Contact for details

Quality Control

Every batch of 5,6-Methano-15-Hydroxy-7,9,11,13-Eicosatetraenoic Acid is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.