Description

2-Piperazineaceticacid,5-Methyl-3,6-Dioxo-,(2S,5S)-(9Ci) is a high-purity chiral piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its specific stereochemistry is critical for biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex molecules targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a constrained scaffold or a functionalized moiety in structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Fine Chemical Synthesis: Employed in the preparation of complex, high-value specialty chemicals requiring specific stereochemical configurations.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical and pharmacological assays.
• Academic Research: Utilized in universities and research institutes for studying asymmetric synthesis methodologies and novel heterocyclic chemistry.

Basic Information

Product Name	2-Piperazineaceticacid,5-Methyl-3,6-Dioxo-,(2S,5S)-(9Ci)
CAS No.	110954-19-3
Molecular Formula	C7H10N2O4
Molecular Weight	186.17 g/mol
Synonyms	(2S,5S)-5-Methyl-3,6-dioxopiperazine-2-acetic acid; (2S,5S)-5-Methyl-3,6-dioxopiperazin-2-ylacetic acid; 2-[(2S,5S)-5-Methyl-3,6-dioxopiperazin-2-yl]acetic acid; (2S,5S)-5-Methyl-2,5-dihydropyrazine-1,4-dione-2-acetic acid; L-5-Methyl-3,6-dioxopiperazine-2-acetic acid; (S,S)-MDOPA; A chiral dioxopiperazine derivative
EINECS	Contact for details

Quality Control

Our 2-Piperazineaceticacid,5-Methyl-3,6-Dioxo-,(2S,5S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (2S,5S)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.