Description

n-Retinoylglycine CAS NO 110848-62-9 is a synthetic retinoid derivative, specifically an amide conjugate of retinoic acid and glycine. This compound is valued for its potential as a biologically active precursor or intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on dermatology, oncology, and metabolic disease studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel retinoid-based therapeutics.
• Biochemical Research: Used as a reference standard or probe in studies of retinoid metabolism and receptor signaling pathways.
• Cosmeceutical R&D: Investigated for potential applications in the development of next-generation anti-aging and skin-rejuvenation actives.
• Cell Differentiation Studies: Employed in in vitro models to study cellular differentiation and proliferation mechanisms.
• API Development: A candidate intermediate in the production of Active Pharmaceutical Ingredients (APIs) targeting nuclear receptors.

Basic Information

Product Name	n-Retinoylglycine
CAS No.	110848-62-9
Molecular Formula	C22H31NO3
Molecular Weight	357.49 g/mol
Synonyms	Retinoylglycine; N-Retinoylglycine; Glycine, N-[(all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoyl]-; (2E,4E,6E,8E)-N-(Carboxymethyl)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenamide; Retinoic Acid Glycine Amide
EINECS	Contact for details

Quality Control

Our n-Retinoylglycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.