Description

2-Fluoromethyl-Piperazine is a specialized fluorinated piperazine derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in the introduction of a reactive fluoromethyl group onto the piperazine scaffold, enabling the synthesis of novel compounds with tailored biological and physicochemical properties. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating new active ingredients and fine-tuning molecular characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable reagent for studying structure-activity relationships (SAR) and introducing fluorine into target molecules to modulate lipophilicity and metabolic stability.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fluorinated fine chemicals and specialty materials.

Basic Information

Product Name	2-Fluoromethyl-Piperazine
CAS No.	110842-63-2
Molecular Formula	C5H11FN2
Molecular Weight	118.15 g/mol
Synonyms	2-(Fluoromethyl)piperazine; 1-(Fluoromethyl)piperazine; Piperazine, 2-(fluoromethyl)-; 2-Fluoromethylpiperazine; 110842-63-2; FC6H11N2; Fluoromethyl piperazine derivative
EINECS	Contact for details

Quality Control

Our 2-Fluoromethyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.