Description

Insulin, Des-Asn(21)-Cys(20)-2,2,2-Trifluoroethylamide(A) is a chemically modified insulin analog designed for advanced research and development. This compound is critical for studying insulin receptor interactions, metabolic pathways, and the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology and diabetes research.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the development of novel insulin analogs and peptide-based therapeutics.
• Biochemical Assay Development: Used as a ligand in receptor binding studies, enzyme-linked immunosorbent assays (ELISAs), and other in vitro diagnostic tests to understand insulin signaling.
• Metabolic Disorder Studies: Employed in preclinical research to investigate insulin action, glucose metabolism, and the pathophysiology of diabetes.
• Structure-Activity Relationship (SAR) Analysis: Provides a modified scaffold for studying the impact of specific amino acid substitutions and fluorinated groups on insulin's potency and stability.
• Academic & Clinical Research: Supports fundamental scientific investigations into hormone-receptor dynamics and potential therapeutic interventions.

Basic Information

Product Name	Insulin, Des-Asn(21)-Cys(20)-2,2,2-Trifluoroethylamide(A)
CAS No.	110613-05-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Des-Asn(21)-Cys(20)-2,2,2-Trifluoroethylamide Insulin (A-Chain); Insulin A-Chain, Des-Asn(21)-Cys(20)-2,2,2-trifluoroethylamide; Modified Insulin A-Chain; Insulin Analog A-Chain Trifluoroethylamide; [Cys20, Des-Asn21]-Insulin A-Chain 2,2,2-trifluoroethylamide; Research Insulin Derivative; Fluorinated Insulin Analog
EINECS	Contact for details

Quality Control

Our Insulin, Des-Asn(21)-Cys(20)-2,2,2-Trifluoroethylamide(A) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the exacting standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.