Description

Insulin, Des-Asn(21)-Cys(20)-Isopropylamide(A)- CAS NO 110485-98-8 is a high-purity, chemically modified insulin analog designed for advanced research and development. This compound is critical for studying insulin receptor binding, metabolic pathways, and the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology and diabetes research.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel insulin analogs and diabetes treatments.
• Biochemical Assay Development: Used in the calibration and validation of bioanalytical methods, including HPLC, LC-MS, and immunoassays, to ensure accurate quantification.
• Metabolic Pathway Studies: Essential for in vitro and in vivo research investigating insulin signaling, glucose uptake mechanisms, and hormone-receptor interactions.
• Structure-Activity Relationship (SAR) Studies: Provides a modified molecular backbone for analyzing how specific structural changes affect insulin's potency and stability.
• Preclinical Formulation Testing: Employed in the development and testing of stable drug delivery systems for peptide-based therapeutics.

Basic Information

Product Name	Insulin, Des-Asn(21)-Cys(20)-Isopropylamide(A)- CAS NO 110485-98-8
CAS No.	110485-98-8
Molecular Formula	C254H377N65O76S6
Molecular Weight	~5807.5 g/mol
Synonyms	Des-Asn(B21)-Cys(B20)-Insulin Isopropylamide; Insulin (Des-Asn21, Cys20) Isopropylamide; Insulin Des-Asn21-Cys20 Isopropylamide; Insulin Analog (Des-Asn21, Cys20, Isopropylamide); B20-Cys, B21-Des-Asn Insulin Isopropylamide; Insulin Isopropylamide Derivative; Research Insulin Analog A
EINECS	Contact for details

Quality Control

Our Insulin, Des-Asn(21)-Cys(20)-Isopropylamide(A)- CAS NO 110485-98-8 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research-grade materials. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature or as specified on the label or CoA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Biological Activity	Assessed by specific assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.