Description

Insulin, Des-Asn(21)-Cysnh2(20)(A)- CAS NO 110485-97-7 is a chemically modified insulin analog, specifically a desamido derivative, used in advanced pharmaceutical research and development. This compound is critical for studying insulin structure-activity relationships, stability, and receptor binding mechanisms. It is primarily utilized by pharmaceutical companies, biotechnology research institutions, and academic laboratories focused on endocrinology, diabetes research, and the development of novel therapeutic peptides.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in insulin and analog manufacturing.
• Biochemical Research: Used in studies investigating the impact of specific amino acid modifications on insulin's biological activity, stability, and aggregation behavior.
• Metabolic Disease Studies: Employed as a tool compound in preclinical research for diabetes and related metabolic disorders to understand insulin signaling pathways.
• Peptide Chemistry Development: Acts as a model substrate in the development and optimization of peptide synthesis, purification, and analysis techniques.
• Formulation Science: Utilized in the development of stable peptide formulations, studying excipient interactions and degradation pathways.

Basic Information

Product Name	Insulin, Des-Asn(21)-Cysnh2(20)(A)-
CAS No.	110485-97-7
Molecular Formula	C254H377N65O76S6
Molecular Weight	~5807.5 g/mol
Synonyms	Desamido Insulin A21; Des-Asn(A21)-Insulin; Insulin (Des-Asn21); Insulin Desamido Analog; A21-Desamido Insulin; Insulin, Desamido(A21)-; [Des-Asn21]-Insulin A-Chain; Research Grade Desamido Insulin
EINECS	Contact for details

Quality Control

Our Insulin, Des-Asn(21)-Cysnh2(20)(A)- is produced under strict quality management systems suitable for research applications. Each batch is characterized using advanced analytical techniques including HPLC, mass spectrometry, and peptide mapping to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, related substances, and analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 10.0%
Peptide Content	≥ 80.0% (by weight)
Biological Activity	Assessed by specific assay (e.g., receptor binding)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.