Description

Perbufylline CAS NO 110390-84-6 is a specialized organic compound belonging to the xanthine derivative class. This high-purity intermediate is valued for its role in advanced pharmaceutical synthesis and research applications. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical and life sciences sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways.
• Research & Development: Used as a reference standard and a critical reagent in medicinal chemistry research for structure-activity relationship (SAR) studies.
• Biochemical Research: Employed in in-vitro studies to investigate its pharmacological effects, such as potential phosphodiesterase (PDE) inhibition.
• Pre-clinical Studies: Serves as a candidate molecule for pharmacokinetic and pharmacodynamic evaluation in drug discovery pipelines.

Basic Information

Product Name	Perbufylline
CAS No.	110390-84-6
Molecular Formula	C13H18N4O3
Molecular Weight	278.31 g/mol
Synonyms	1,3-Dimethyl-8-(3-oxobutyl)xanthine; 8-(3-Oxobutyl)-1,3-dimethylxanthine; 1,3-Dimethyl-8-(3-oxobutyl)-3,7-dihydro-1H-purine-2,6-dione; HWA 448
EINECS	Contact for details

Quality Control

Our Perbufylline is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be aligned with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.