Description

(3R,6R)-6-Methylpiperidine-3-Carboxylic Acid Hydrochloride is a high-purity chiral piperidine derivative, a crucial building block in modern pharmaceutical synthesis. Its defined stereochemistry makes it an essential intermediate for creating active pharmaceutical ingredients (APIs) with specific biological activity. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry influences biological efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Incorporated into peptide backbones to create stable, biologically active mimetics with enhanced metabolic stability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	(3R,6R)-6-Methylpiperidine-3-Carboxylic Acid Hydrochloride
CAS No.	110287-78-0
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	(3R,6R)-6-Methyl-3-piperidinecarboxylic acid hydrochloride; (3R,6R)-6-Methylnipecotic acid hydrochloride; (3R,6R)-6-Methylpiperidine-3-carboxylic acid HCl; (3R,6R)-3-Carboxy-6-methylpiperidine hydrochloride; (3R,6R)-6-Methyl-3-piperidinecarboxylic acid HCl salt; (3R,6R)-6-Methylnipecotate hydrochloride; (3R,6R)-6-Methyl-3-piperidinecarboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our (3R,6R)-6-Methylpiperidine-3-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.