Description

2,3-Methylene Penam is a specialized penam derivative, a key structural motif in advanced pharmaceutical chemistry. This compound serves as a crucial synthetic intermediate for the development of novel β-lactam antibiotics and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of new antimicrobial agents and the exploration of structure-activity relationships.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel penam and carbapenem antibiotic analogs.
• Antimicrobial Research: Used in R&D for developing new compounds to combat antibiotic-resistant bacterial strains.
• Chemical Synthesis: Serves as a precursor for complex heterocyclic compounds in medicinal chemistry programs.
• Academic Research: Employed in university and institutional labs for studying β-lactam chemistry and reactivity.
• Process Development: Used in scaling up synthetic routes for potential active pharmaceutical ingredients (APIs).
• Bioconjugation Studies: Potential use in creating targeted drug delivery systems due to its reactive bicyclic structure.

Basic Information

Product Name	2,3-Methylene Penam
CAS No.	110220-97-8
Molecular Formula	C7H9NO2S
Molecular Weight	171.22 g/mol
Synonyms	2,3-Methylenepenam; 2,3-Methylene-1-azabicyclo[3.2.0]heptane-4-carboxylic acid, 7-oxo-; 2,3-Methylenepenam-4-carboxylic acid; Penam, 2,3-methylene-; 1-Azabicyclo[3.2.0]heptane-4-carboxylic acid, 2,3-methylene-7-oxo-; (2S,5R)-2,3-Methylenepenam-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2,3-Methylene Penam is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While typically supplied as a research-grade material, production can be aligned with cGMP guidelines for advanced development stages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.