Description

(Isopropyloxycarbonylmethylene)Triphenylphosphorane CAS NO 110212-61-8 is a specialized Wittig reagent, a key organophosphorus compound used in synthetic organic chemistry. Its primary value lies in its ability to facilitate the efficient and stereoselective synthesis of alkenes from carbonyl compounds, a fundamental transformation in constructing complex molecular architectures. This high-purity reagent is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable and consistent performance in sensitive synthetic sequences.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for constructing olefin linkages in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Production: Used in the preparation of key intermediates for herbicides, fungicides, and insecticides that require specific alkene functionalities.
• Fine Chemical Manufacturing: Enables the production of specialty chemicals, flavors, fragrances, and liquid crystals through controlled olefination reactions.
• Academic & Industrial R&D: A staple tool in research laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Material Science: Potential use in the synthesis of organic semiconductors, polymers, and other advanced materials with tailored properties.

Basic Information

Product Name	(Isopropyloxycarbonylmethylene)Triphenylphosphorane
CAS No.	110212-61-8
Molecular Formula	C23H23O2P
Molecular Weight	362.40 g/mol
Synonyms	Isopropyl (triphenylphosphoranylidene)acetate; (Isopropoxycarbonylmethylene)triphenylphosphorane; Triphenylphosphoranylideneacetic Acid Isopropyl Ester; Acetic acid, 2-(triphenylphosphoranylidene)-, 1-methylethyl ester; Wittig reagent (isopropyl ester variant); Phenylphosphorane, [(1-methylethoxy)carbonyl]methylene]triphenyl-; (Carboxyisopropylmethylidene)triphenylphosphorane
EINECS	Contact for details

Quality Control

Our production of (Isopropyloxycarbonylmethylene)Triphenylphosphorane adheres to stringent quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes comprehensive analysis, including NMR (¹H and ³¹P) and HPLC for identity and purity verification. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters to support your quality management systems. Our commitment to cGMP principles in manufacturing ensures a reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures will compromise its purity and reactivity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.