Description

Homopahutoxin is a potent marine-derived neurotoxin structurally related to the pahutoxins, known for its specific ion channel activity. This high-purity reference standard is critical for advanced pharmacological research and the development of novel bioactive compounds. It serves as an essential tool for neuroscientists, toxicologists, and pharmaceutical R&D teams investigating sodium channel modulation, marine toxin mechanisms, and potential therapeutic applications.

Application

• Neuroscience Research: A key reference standard for studying the modulation and blocking mechanisms of voltage-gated sodium channels (VGSCs) in neuronal cells.
• Toxicology & Safety Assessment: Used in the identification, quantification, and toxicological profiling of marine toxins in environmental and food safety testing.
• Pharmaceutical Development: Serves as a lead compound or molecular template for the discovery and synthesis of new analgesic or neuroprotective agents.
• Academic & Institutional Research: Provides a critical reagent for universities and research institutes exploring the structure-activity relationships (SAR) of neuroactive natural products.
• Biochemical Assay Development: Employed as a control and calibration standard in high-throughput screening (HTS) assays targeting ion channel function.
• Marine Natural Product Chemistry: Used as an analytical standard for the isolation, characterization, and synthesis of related pahutoxin analogues.

Basic Information

Product Name	Homopahutoxin
CAS No.	109777-68-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Homopahutoxin; Pahutoxin analogue; Marine neurotoxin; Sodium channel toxin; Ichthyotoxin; Pardaxin analogue; (3S,6S,9S,12S,18S,21S,24S,27S,30S,33S)-3,6,9,12,15,18,21,24,27,30,33-Undecaazatetracyclo[30.3.1.1¹⁴,¹⁷.1²⁰,²³]hexatriacontane-1(35),2,4,7,10,13,16,19,22,25,28,31,34-tetradecaene-4,7,10,13,16,19,22,25,28,31,34-undecacarboxylic acid (IUPAC-style); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Homopahutoxin is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including chromatographic purity analysis and structural confirmation. A detailed Certificate of Analysis (COA), providing full specification data, is supplied with every shipment to guarantee traceability and meet the stringent requirements of advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. For long-term storage, keep desiccated under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.