Description

Piperazinium, 4-Carboxy-1-(2-Heptynyl)-1-Methyl-, Bromide, Ethyl Ester is a specialized quaternary ammonium salt derivative of piperazine, valued for its unique structural features including a terminal alkyne and an ester group. This compound is a critical high-purity intermediate in advanced organic synthesis, particularly for pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological or anti-infective pathways.
• Agrochemical Research: Used in the development of new generation herbicides, fungicides, or plant growth regulators where the piperazine moiety is required.
• Chemical Biology & Proteomics: The alkyne functionality enables its use in click chemistry applications, such as Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC), for bioconjugation and probe development.
• Ligand & Catalyst Synthesis: Acts as a precursor for creating specialized ligands or ionic liquids used in catalytic systems and material science.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in organic chemistry and medicinal chemistry programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular scaffold.

Basic Information

Product Name	Piperazinium, 4-Carboxy-1-(2-Heptynyl)-1-Methyl-, Bromide, Ethyl Ester
CAS No.	109699-57-2
Molecular Formula	C16H27BrN2O2
Molecular Weight	359.31 g/mol
Synonyms	1-(2-Heptynyl)-1-methyl-4-carboxypiperazinium bromide ethyl ester; 4-Carboxy-1-(2-heptynyl)-1-methylpiperazinium bromide ethyl ester; Ethyl 1-(2-heptynyl)-1-methylpiperazin-1-ium-4-carboxylate bromide; 1-Methyl-1-(2-heptynyl)piperazin-1-ium-4-carboxylic acid ethyl ester bromide; Piperazinium, 1-(2-heptynyl)-1-methyl-4-carboxy-, bromide, ethyl ester; (2-Heptynyl)methyldiethylenediammonium bromide carboxylate ethyl ester; N-(2-Heptynyl)-N-methylpiperazinium-4-carboxylate ethyl ester bromide
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We employ state-of-the-art analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment. Our quality protocols are designed to meet the stringent requirements of cGMP for pharmaceutical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.