Description

3-Hydroxypropanoyl Chloride is a versatile and highly reactive acid chloride derivative of 3-hydroxypropanoic acid. This compound is a critical building block in organic synthesis, valued for its ability to introduce the 3-hydroxypropanoyl moiety into target molecules efficiently. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of active pharmaceutical ingredients (APIs), advanced intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a hydroxy acid functionality.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and plant growth regulators where its reactive chloride group facilitates coupling reactions.
• Polymer & Material Science: Serves as a monomer or modifying agent for producing specialty polyesters, polyamides, and other functional polymers.
• Peptide & Protein Chemistry: Employed as an acylating agent for modifying amino acids or for introducing specific side chains in peptide synthesis.
• Ligand & Catalyst Development: Useful in the preparation of complex ligands and organometallic catalysts for asymmetric synthesis.
• Crosslinking Agent: Functions as a reactive crosslinker in the formulation of coatings, adhesives, and resins to enhance material properties.

Basic Information

Product Name	3-Hydroxypropanoyl Chloride
CAS No.	109608-73-3
Molecular Formula	C3H5ClO2
Molecular Weight	108.52 g/mol
Synonyms	3-Hydroxypropionyl Chloride; β-Hydroxypropionyl Chloride; Hydroxypropanoic Acid Chloride; 3-Hydroxypropanoic Acid Chloride; 3-Hydroxypropanoyl Chloride; 3-Hydroxypropionic Acid Chloride; NSC 403809; 109608-73-3
EINECS	Contact for details

Quality Control

Our 3-Hydroxypropanoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by titration and impurity profiling by gas chromatography (GC) or HPLC, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, confirming compliance with customer requirements and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) to minimize degradation and volatility. Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC/HPLC)	≤ 2.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.