Description

1-(4-Bromophenyl)-2-(Piperazin-1-Yl)Ethanone is a high-purity brominated aromatic ketone derivative featuring a piperazine moiety, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) agents, kinase inhibitors, and other receptor-targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce the 4-bromophenyl and piperazine pharmacophores into novel chemical entities.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and pesticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems or as a scaffold in material science.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	1-(4-Bromophenyl)-2-(Piperazin-1-Yl)Ethanone
CAS No.	109607-56-9
Molecular Formula	C12H15BrN2O
Molecular Weight	283.17 g/mol
Synonyms	2-(4-Bromophenyl)-2-oxoethylpiperazine; 1-[2-(4-Bromophenyl)-2-oxoethyl]piperazine; 2-(4-Bromobenzoyl)ethylpiperazine; 4-Bromophenacyl piperazine; N-(2-Oxo-2-(4-bromophenyl)ethyl)piperazine; 109607-56-9; 1-(4-Bromophenyl)-2-(piperazin-1-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(4-Bromophenyl)-2-(Piperazin-1-Yl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity assessment. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.