Description

11(R)-Hepe is a specialized, high-purity eicosapentaenoic acid (EPA) derivative, a key intermediate in the synthesis of bioactive lipid mediators. This compound matters for its role as a precursor in the production of specialized pro-resolving mediators (SPMs), which are critical for modulating inflammatory responses and promoting tissue repair. It is primarily needed by pharmaceutical R&D teams, advanced nutraceutical manufacturers, and academic research institutions focused on inflammation, immunology, and metabolic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of advanced anti-inflammatory and pro-resolving drug candidates.
• Biochemical Research: Used as a reference standard and substrate in studies of eicosanoid and resolvin biosynthesis pathways.
• Nutraceutical Development: Serves as a high-purity ingredient for advanced dietary supplements targeting metabolic and inflammatory health.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate lipid signaling mechanisms and cellular responses.
• Analytical Standard: Employed as a certified reference material (CRM) for HPLC, GC, and LC-MS method development and validation in analytical laboratories.

Basic Information

Product Name	11(R)-Hepe
CAS No.	109430-11-7
Molecular Formula	C₂₀H₃₀O₃
Molecular Weight	318.45 g/mol
Synonyms	(11R)-Hydroxy-5Z,8Z,12E,14Z,17Z-eicosapentaenoic Acid; 11(R)-HEPE; 11R-Hydroxy-5,8,12,14,17-eicosapentaenoic Acid; 11R-HEPE; (11R)-HEPE; 11(R)-Hydroxyeicosapentaenoic Acid; 11R-Hydroxyeicosapentaenoic Acid; 11(R)-HETE (Note: This is a common but less specific synonym)
EINECS	Contact for details

Quality Control

Every batch of 11(R)-Hepe is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) that include data from chiral HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% (11R-isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.