Description

Englitazone Sodium is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant interest for its role in the development of novel therapeutic agents, particularly in metabolic and endocrine research. It is primarily utilized by pharmaceutical manufacturers, biotechnology R&D laboratories, and academic research institutions engaged in drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced thiazolidinedione-based drug candidates.
• Metabolic Research: Used as a reference standard or active compound in studies targeting PPARγ (Peroxisome Proliferator-Activated Receptor Gamma) pathways.
• Drug Discovery & Development: Serves as a crucial precursor or analog in medicinal chemistry programs for diabetes and related metabolic disorders.
• Biochemical Assays: Employed in in vitro screening assays to evaluate potency and selectivity of new chemical entities.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and mechanism-of-action investigations.
• Reference Standard: Sourced by analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.

Basic Information

Product Name	Englitazone Sodium
CAS No.	109229-57-4
Molecular Formula	C19H19N2NaO3S
Molecular Weight	378.42 g/mol
Synonyms	Englitazone Sodium Salt; 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione Sodium Salt; Ciglitazone Sodium Salt Analog; Sodium 5-((4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione); PPARγ Agonist Sodium Salt; TZD Sodium Derivative; ENG Sodium
EINECS	Contact for details

Quality Control

Our Englitazone Sodium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent control of residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.