Description

Methyl 3-Chloro-5-Phenylpyrazine-2-Carboxylate is a high-purity, synthetically valuable heterocyclic building block. This compound is critical for advanced organic synthesis, serving as a versatile intermediate in the development of complex molecules. It is primarily used by research institutions and pharmaceutical companies engaged in medicinal chemistry and agrochemical discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrazine core's bioactivity.
• Material Science: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: An essential reagent for constructing complex heterocyclic frameworks in academic and industrial R&D laboratories.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Methyl 3-Chloro-5-Phenylpyrazine-2-Carboxylate
CAS No.	109019-16-1
Molecular Formula	C12H9ClN2O2
Molecular Weight	248.66 g/mol
Synonyms	Methyl 3-chloro-5-phenylpyrazine-2-carboxylate; 3-Chloro-5-phenylpyrazine-2-carboxylic acid methyl ester; Methyl 3-chloro-5-phenyl-2-pyrazinecarboxylate; 2-Pyrazinecarboxylic acid, 3-chloro-5-phenyl-, methyl ester; 109019-16-1; Methyl 3-chloro-5-phenylpyrazinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-5-Phenylpyrazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.