Description

Trimethylamine-15N Hydrochloride is a stable, isotopically labeled salt of trimethylamine, where the nitrogen atom is enriched with the 15N isotope. This compound is essential for advanced research and analytical applications requiring precise molecular tracing and quantification. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and academic research sectors for applications such as NMR spectroscopy, mass spectrometry, and metabolic pathway studies.

Application

• NMR Spectroscopy: Serves as a crucial internal standard or reference compound for 15N nuclear magnetic resonance studies, providing high-resolution structural and dynamic information.
• Mass Spectrometry: Used as a stable isotope-labeled internal standard for the accurate quantification of trimethylamine and related metabolites in complex biological matrices.
• Metabolic Research: Enables the tracing of nitrogen pathways in biological systems, facilitating studies on choline metabolism, gut microbiome activity, and disease biomarkers.
• Pharmaceutical Development: Employed in the research and quality control of drug candidates, particularly those involving quaternary ammonium compounds or requiring isotopic labeling for pharmacokinetic studies.
• Chemical Synthesis: Acts as a labeled building block for the synthesis of more complex 15N-labeled compounds for research purposes.
• Environmental & Food Science: Applied in trace analysis and studies concerning trimethylamine-N-oxide (TMAO) and its role in food spoilage or environmental processes.

Basic Information

Product Name	Trimethylamine-15N Hydrochloride
CAS No.	108451-51-0
Molecular Formula	C3H915N•HCl
Molecular Weight	96.57 g/mol (for 15N labeled form)
Synonyms	N-Trimethylamine-15N Hydrochloride; TMA-15N HCl; (15N)Trimethylamine Hydrochloride; Trimethylamine-15N HCl; 15N-Trimethylammonium Chloride; (Methyl-15N)trimethylammonium Chloride; Me315N•HCl
EINECS	Contact for details

Quality Control

Our Trimethylamine-15N Hydrochloride is produced and tested under strict quality management protocols. Each batch is characterized to ensure high chemical purity and isotopic enrichment, typically exceeding 98% chemical purity and 99 atom % 15N. Certificates of Analysis (COA) detailing specifications for assay, isotopic enrichment, identity (IR, NMR), and impurity profiles are provided with every shipment to guarantee reproducibility and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0%
15N Isotopic Enrichment	≥ 99 atom %
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.