Description

5-n-(3-Aminophenyl)Amiloride is a specialized chemical derivative of the diuretic agent amiloride, designed for advanced research and development applications. This compound is valued for its role as a potent and selective inhibitor of specific ion transport mechanisms, making it a critical tool in biochemical and pharmacological studies. It is primarily utilized by researchers and development scientists in the pharmaceutical, biotechnology, and life sciences sectors for investigating cellular processes and developing novel therapeutic agents.

Application

• Biochemical Research: Used as a selective inhibitor in studies of sodium ion channels and epithelial sodium transport mechanisms.
• Pharmacological Development: Serves as a key intermediate or reference standard in the development of new diuretic or cardiovascular drugs.
• Cell Biology Studies: Employed to investigate ion flux, cell volume regulation, and related signaling pathways in vitro.
• Academic Research: Utilized in university and institutional labs for fundamental research into membrane transport proteins.
• High-Throughput Screening (HTS): Acts as a reference compound in drug discovery campaigns targeting ion channels.

Basic Information

Product Name	5-n-(3-Aminophenyl)Amiloride
CAS No.	108414-87-5
Molecular Formula	C12H12ClN7O
Molecular Weight	305.72 g/mol
Synonyms	5-(N-3-Aminophenyl)amiloride; 3-Amino-5-(diaminomethylideneamino)-N-(diaminomethylidene)-6-chloropyrazine-2-carboxamide; 5-(3-Aminophenylamino)-6-chloro-N-(diaminomethylene)pyrazine-2-carboxamide; 5-(3-Aminophenyl)amiloride; 5-N-(3-Aminophenyl)amiloride; Amiloride, 5-(3-aminophenyl)-; Benzamil analog
EINECS	Contact for details

Quality Control

Our 5-n-(3-Aminophenyl)Amiloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.