Description

(E)-2-[n-[(2S)-2,3-Dihydroxy-1-Oxopropyl]-D-Serylamino]-n-[(3R)-2-Oxo-1-Sulfo-3-Azetidinyl]-2-Butenediamide is a high-purity, synthetically derived azetidinone derivative with a complex molecular architecture. This compound is of significant interest for its role as a key synthetic intermediate or a potential pharmacophore in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly in the fields of enzyme inhibition and targeted drug design.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), especially β-lactam analogs.
• Biochemical Research: Used as a reference standard or a substrate analog in enzymatic studies and proteomics research to investigate binding mechanisms.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies aimed at developing new inhibitors for specific biological targets.
• Process Development: Employed in the optimization of synthetic routes and scale-up processes within pilot plants and kilo-labs.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	(E)-2-[n-[(2S)-2,3-Dihydroxy-1-Oxopropyl]-D-Serylamino]-n-[(3R)-2-Oxo-1-Sulfo-3-Azetidinyl]-2-Butenediamide
CAS No.	108065-95-8
Molecular Formula	C13H19N3O10S
Molecular Weight	409.37 g/mol
Synonyms	D-Seryl-N-[(3R)-2-oxo-1-sulfo-3-azetidinyl]-N-[(1S)-2,3-dihydroxy-1-oxopropyl]-(E)-2-butenamide; (E)-2-{N-[(2S)-2,3-Dihydroxypropanoyl]-D-serylamino}-N-[(3R)-2-oxo-1-sulfoazetidin-3-yl]but-2-enediamide; Azetidinone sulfonic acid derivative; Butenediamide, 2-[N-[(2S)-2,3-dihydroxy-1-oxopropyl]-D-serylamino]-N-[(3R)-2-oxo-1-sulfo-3-azetidinyl]-, (E)-; CAS 108065-95-8
EINECS	Contact for details

Quality Control

Our (E)-2-[n-[(2S)-2,3-Dihydroxy-1-Oxopropyl]-D-Serylamino]-n-[(3R)-2-Oxo-1-Sulfo-3-Azetidinyl]-2-Butenediamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.